Reduces the Need for BPH Related Surgery

Composition : Dutasteride 0.5mg & Silodosine 4mg.

Form : Tablets / Pack : 10 x 10's / Type : ALU-ALU

Description : Dutasteride inhibits the conversion of testosterone to Di-hydrotestosterone (DHT). Testosterone is converted to DHT by the enzyme 5- Alpha-reductase, which exists in two iso-forms.The type-2 iso-enzyme is primarily active in the reproductive tissues, while type- 1 iso-enzyme is responsible for testosterone conversion in the skin and liver. Dutasteride competitively & specificifically inhibits both type of 5- alpha-reductase. Silodosin belongs to a class of selective alpha-1A adrenergic receptor blockers, works by blocking the alpha-1A adrenergic receptors located in the muscles of prostate gland, urinary bladder & urethra and hence relaxes these muscles, resulting in an improvement in urine flow & a reduction in BPH symptoms. Silodosin has a very high uro-selectivity i.e. selectivity for the prostate.

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