Mictura-4
Reduces the Need for BPH Related Surgery


Composition : Silodosine 4mg.

Form : Tablets / Pack : 10 x 10's / Type : ALU-ALU

Description : Silodosin, is a medication for the symptomatic treatment of benign prostatic hyperplasia. It acts as an α1A-adrenoceptor antagonist with high uroselectivity (selectivity for the prostate), has been approved by the FDA since October 2008 at a recommended dose of 8 mg orally once daily. Clinical studies have shown that this selective α1A-AR is very attractive and more effective than placebo for voiding and storage symptoms in LUTS arising from BPH. Silodosin has excellent early efficacy, and is at least as effective as for other α1-blockers. Silodosin distinguishes itself by a strong effect not only on symptoms but also on obstruction as measured by pressure flow studies- Drug Des Devel Ther. 2010; 4: 291–297.

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Mictura-8
Reduces the Need for BPH Related Surgery


Composition : Silodosine 8mg.

Form : Tablets / Pack : 10 x 10's / Type : ALU-ALU

Description : Silodosin, is a medication for the symptomatic treatment of benign prostatic hyperplasia. It acts as an α1A-adrenoceptor antagonist with high uroselectivity (selectivity for the prostate), has been approved by the FDA since October 2008 at a recommended dose of 8 mg orally once daily. Clinical studies have shown that this selective α1A-AR is very attractive and more effective than placebo for voiding and storage symptoms in LUTS arising from BPH. Silodosin has excellent early efficacy, and is at least as effective as for other α1-blockers. Silodosin distinguishes itself by a strong effect not only on symptoms but also on obstruction as measured by pressure flow studies- Drug Des Devel Ther. 2010; 4: 291–297.

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Mictura-DS
Reduces the Need for BPH Related Surgery


Composition : Dutasteride 0.5mg & Silodosine 4mg.

Form : Tablets / Pack : 10 x 10's / Type : ALU-ALU

Description : Dutasteride inhibits the conversion of testosterone to Di-hydrotestosterone (DHT). Testosterone is converted to DHT by the enzyme 5- Alpha-reductase, which exists in two iso-forms.The type-2 iso-enzyme is primarily active in the reproductive tissues, while type- 1 iso-enzyme is responsible for testosterone conversion in the skin and liver. Dutasteride competitively & specificifically inhibits both type of 5- alpha-reductase. Silodosin belongs to a class of selective alpha-1A adrenergic receptor blockers, works by blocking the alpha-1A adrenergic receptors located in the muscles of prostate gland, urinary bladder & urethra and hence relaxes these muscles, resulting in an improvement in urine flow & a reduction in BPH symptoms. Silodosin has a very high uro-selectivity i.e. selectivity for the prostate.

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Alsone Syrup
Maintains Acid-Base Balance


Composition : Sodium Hydrogen Citrate 1.4gm/ 5ml SUGAR FREE

Form : Syrup / Pack : 1 x 10ml / Type : PVC Bottle

Description : Di Sodium Hydrogen Citrate is an acid salt of citric acid used as an antioxidant as well as to improve the effects of other antioxidants. Also used as an acidity regulator and sequestrant. Thus known as systemic alkalinizer, make the urine less acidic , thus helps the kidneys get rid of uric acid, helping to prevent gout and certain types of kidney stones (urate), also prevent and treat certain metabolic problems (acidosis) caused by kidney disease. Also alleviate discomfort from certain urinary tract infections.

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Sobitab- 500
The Quick Acting Antacid since Then


Composition : Sodium Bi Carbonate 500mg

Form : Tablets / Pack : 10's / Type : Blister

Description : Randomly assigned 134 adult patients with CKD (creatinine clearance [CrCl] 15 to 30 ml/min per 1.73 m2) and serum bicarbonate 16 to 20 mmol/L to either supplementation with oral sodium bicarbonate or standard care for 2 yr. The primary end points were rate of CrCl decline, the proportion of patients with rapid decline of CrCl (>3 ml/min per 1.73 m2/yr), and ESRD (CrCl <10 ml/min). Secondary end points were dietary protein intake, normalized protein nitrogen appearance, serum albumin, and mid-arm muscle circumference. Compared with the control group, decline in CrCl was slower with bicarbonate supplementation (5.93 versus 1.88 ml/min 1.73 m2; P < 0.0001). Patients supplemented with bicarbonate were significantly less likely to experience rapid progression (9 versus 45%; relative risk 0.15; 95% confidence interval 0.06 to 0.40; P < 0.0001). Similarly, fewer patients supplemented with bicarbonate developed ESRD (6.5 versus 33%; relative risk 0.13; 95% confidence interval 0.04 to 0.40; P < 0.001). Nutritional parameters improved significantly with bicarbonate supplementation, which was well tolerated. This study demonstrates that bicarbonate supplementation slows the rate of progression of renal failure to ESRD and improves nutritional status among patients with CKD- Journal of the American Society of Nephrology 2009.

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Sobitab-1000
The Quick Acting Antacid since Then


Composition : Sodium Bi Carbonate 1000mg

Form : Tablets / Pack : 10's / Type : Blister

Description : Randomly assigned 134 adult patients with CKD (creatinine clearance [CrCl] 15 to 30 ml/min per 1.73 m2) and serum bicarbonate 16 to 20 mmol/L to either supplementation with oral sodium bicarbonate or standard care for 2 yr. The primary end points were rate of CrCl decline, the proportion of patients with rapid decline of CrCl (>3 ml/min per 1.73 m2/yr), and ESRD (CrCl <10 ml/min). Secondary end points were dietary protein intake, normalized protein nitrogen appearance, serum albumin, and mid-arm muscle circumference. Compared with the control group, decline in CrCl was slower with bicarbonate supplementation (5.93 versus 1.88 ml/min 1.73 m2; P < 0.0001). Patients supplemented with bicarbonate were significantly less likely to experience rapid progression (9 versus 45%; relative risk 0.15; 95% confidence interval 0.06 to 0.40; P < 0.0001). Similarly, fewer patients supplemented with bicarbonate developed ESRD (6.5 versus 33%; relative risk 0.13; 95% confidence interval 0.04 to 0.40; P < 0.001). Nutritional parameters improved significantly with bicarbonate supplementation, which was well tolerated. This study demonstrates that bicarbonate supplementation slows the rate of progression of renal failure to ESRD and improves nutritional status among patients with CKD- Journal of the American Society of Nephrology 2009.

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