Luvastab- 40
A Highly Attractive Option For ASCVD

Composition : Fluvastatin 40mg

Form : Tablets / Pack : 1 X 10's / Type : AA

Description : One‐hundred and forty‐five trials (36 placebo controlled and 109 before and after) evaluated the dose‐related efficacy of fluvastatin in 18,846 participants. The participants were of any age with and without evidence of cardiovascular disease, and fluvastatin effects were studied within a treatment period of three to 12 weeks. Log dose‐response data over doses of 2.5 mg to 80 mg revealed strong linear dose‐related effects on blood total cholesterol and LDL cholesterol and a weak linear dose‐related effect on blood triglycerides. There was no dose‐related effect of fluvastatin on blood HDL cholesterol. Fluvastatin 10 mg/day to 80 mg/day reduced LDL cholesterol by 15% to 33%, total cholesterol by 11% to 25% and triglycerides by 3% to 17.5%. For every two‐fold dose increase there was a 6.0% (95% CI 5.4 to 6.6) decrease in blood LDL cholesterol, a 4.2% (95% CI 3.7 to 4.8) decrease in blood total cholesterol and a 4.2% (95% CI 2.0 to 6.3) decrease in blood triglycerides. The quality of evidence for these effects was judged to be high - Cochrane Database of Systematic Reviews - Published : 06 March 2018

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