Ipraduo Respules
The Algorithm Of Asthma Management


Composition : Levosalbutamol 1.25mg + Ipratropium Bromide Respule

Form : Respirator Solution / Pack : 10 x 5 x 2.5ml / Type : Combipack Respules

Description : Levosalbutamol being a functional short-acting Beta 2 adrenergic receptor agonist, relaxes the smooth muscles from the trachea to the terminal bronchioles. Increased cyclic AMP concentrations are also associated with the inhibition of the release of mediators from mast cells in the airways, irrespective of the spasmogen involved, thereby protecting against all broncho-constrictor challenges.
Ipratropium Bromide (IB) specifically has emerged as the overwhelming choice of pulmonologists and emergency physicians because of its limited systemic absorption from the lungs when given as an inhaled preparation. However, although the varying trials, predominantly in the emergency department setting, have typically shown a trend toward improved outcomes - Pediatr Emerg Care. 2009 Oct; 25(10):687-92.

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Vodaryl-200 Inhaler
The Algorithm Of Asthma Management


Composition : Budesonide 200mcg per Actuation

Form : Inhaler / Pack : 1 X 1's / Type : 120 Metered Doses

Description : Budesonide inhaler is used to prevent difficulty breathing, chest tightness, wheezing, and coughing caused by asthma. Budesonide powder for oral inhalation is used in adults and children 6 years of age and older. Budesonide is a potent glucocorticoid that binds with high affinity to the glucocorticoid receptor. It has a high ratio of topical to systemic activity.. Vodaryl -200 inhaler is designed to provide 120 inhalations. After 120 inhalations the device may not contain the correct amount of medication, so keep record of the number of inhalations used.

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Vodaryl Respules – 1mg
The Algorithm Of Asthma Management


Composition : Budesonide 1mg per Respule

Form : Respirator Suspension / Pack : 5 x 5 x 2ml / Type : Combipack Respules

Description : Budesonide is a potent glucocorticoid that binds with high affinity to the glucocorticoid receptor. It has a high ratio of topical to systemic activity. Budesonide is used to control and prevent symptoms such as wheezing, shortness of breath caused by asthma. Used as maintenance treatment of asthma and as a prophylactic therapy in children 12 months to 8 years of age

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Vodaryl-200FB Inhaler
The Algorithm Of Asthma Management


Composition : Formoterol Fumarate 6mcg + Budesonide 200mcg Per Actuation

Form : Inhaler / Pack : 1 x 1's / Type : 120 Metered Doses

Description : Formoterol is a very potent, long-acting, beta-2 adrenoceptor-agonist with a high intrinsic activity and a rapid onset of action Where as Budesonide is a potent glucocorticoid that binds with high affinity to the glucocorticoid receptor. It has a high ratio of topical to systemic activity. The combination medicine has different modes of action and show additive effects in terms of reduction of asthma exacerbations thus used to control and prevent the symptoms of asthma in adults and children above 6 years old. Formoterol & Budesonide is also used to help control the symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis

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Acmon-200
Ensure Unconditional Breath Round The Clock


Composition : Acebrophylline 200mg Sustained Release

Form : Tablets / Pack : 10 x 10"s / Type : ALU ALU

Description : Acebrophylline is an airway mucus regulator with antiinflammatory action. The drug's approach involves several points of attack in obstructive airway disease. The molecule contains ambroxol, which facilitates various steps in the biosynthesis of pulmonary surfactant, theophylline-7 acetic acid whose carrier function raises blood levels of ambroxol, thus rapidly and intensely stimulating surfactant production. The resulting reduction in the viscosity and adhesivity of the mucus greatly improves ciliary clearance. By deviating phosphatidylcholine towards surfactant synthesis, making it no longer available for the synthesis of inflammatory mediators such as the leukotrienes, acebrophylline also exerts an inflammatory effect. This is confirmed in vivo by the reduction in aspecific bronchial hyper-responsiveness in patients with stable bronchial asthma. On a clinical level, acebrophylline is therapeutically effective in patients with acute or chronic bronchitis, chronic obstructive or asthma-like bronchitis and recurrence of chronic bronchitis; it reduces the frequency of episodes of bronchial obstruction and reduces the need for beta2-agonists, and improves indexes of ventilatory function- Monaldi Arch Chest Dis. 2007 Jun;67(2):106-15.

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Kleputab – FM
When Come Across Smarty Eyes


Composition : Fexofenadine 120mg + Montelukast 10mg

Form : Tablets / Pack : 1 X 10s / Type : Strips

Description : The literature search establishes that addition of fexofenadine to montelukast has added benefit. The combination therapy of montelukast with fexofenadine provide enhancing and complimentary effects thereby reducing the symptoms effectively- – Indian journal of Pharmacology; 2016; Vol : 48; Issue : 6; Page : 649-653
Fexofenadine 120 mg + Montelukast 10mg fixed dose combination (FDC) was bioequivalent to individual tablets of fexofenadine & montelukast of the same strengths administered concurrently. No serious AEs were observed with fexofenadine 120mg + montelukast 10mg FDC. The tolerability of the FDC was comparable to that of the co-administered individual components. With the availability of an FDC tablet, patients suffering from allergic rhinitis will have a more convenient option to improve treatment compliance and adherence - Indian Journal of Pharmaceutical Sciences, pp 651- 656, Sept.- Oct. 2016

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Kleputab- LM
Reduces The Symptoms Effectively


Composition : Levocetrizine 5mg + Montelukast 10mg

Form : Strips / Pack : 1 X 10s / Type : Strips

Description : Compared with montelukast monotherapy, montelukast plus levocetirizine demonstrated a significant reduction in MDNSS (least squares mean ± standard error of combination vs montelukast, –0.98±0.06 vs –0.81±0.06, respectively; P = .045). Regarding all other allergic rhinitis efficacy end points, the combination therapy group experienced greater improvements compared with the montelukast monotherapy group. Similar results were reported with respect to overall assessment scores, as well as FEV1, FVC, FEV1/FVC, and ACT score changes from baseline in the 2 treatment arms. Montelukast plus levocetirizine was well tolerated, with a safety profile similar to that reported for montelukast monotherapy. The investigators concluded that the fixed-dose combination of montelukast plus levocetirizine was effective and safe for the treatment of perennial allergic rhinitis and asthma - Pulmonology Advisor‘s- CHEST 2018

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Acmon- FX
The Engineered FDC Formulation


Composition : Acebrophylline 200mg SR+ Fexofenadine 120mg+ Montilukast 10mg

Form : Tablets / Pack : 1 X 10s / Type : AA

Description : The literature search establishes that addition of fexofenadine to montelukast has added benefit. The combination therapy of montelukast with fexofenadine provide enhancing and complimentary effects thereby reducing the symptoms effectively- Indian journal of Pharmacology; 2016; Vol : 48; Issue : 6; Page : 649-653 A comparable clinical improvement of symptoms score and spirometric parameters with both the drugs (Acebrophylline vs Sustained Release Theophylline) has been observed (p-value>0.05). Amount of sputum, frequency of use of reliever medication and dyspnoea showed improvement with both the drugs but cardiovascular side effects are less with Acebrophylline - J Clin Diagn Res. 2014 Sep;8(9)

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Cogvgard Inhaler
The Algorithm Of Asthma Management


Composition : Tritropium Bromide 9mcg Per Actuation

Form : Inhaler / Pack : 1 x 1's / Type : 120 Metered Doses

Description : : In large randomized clinical trials enrolling patients with moderate to severe asthma, add-on therapy with Tiotropium has demonstrated to be efficacious in improving lung function, decreasing risk of exacerbation and slowing the worsening of disease In view of the numerous ancillary effects acting on inflammation, airway remodeling, mucus production and cough reflex, along with the good safety profile and the broad spectrum of efficacy demonstrated in different disease phenotypes, tiotropium can represent a beneficial alternative in the therapeutic management of poorly controlled asthma - Multidiscip Respir Med 12, 12 (2017).

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Xodil-DX
Protects Body From Exhaustion


Composition : Dextromethorphan HBr 10mg; Chlorpheniramine Maleate 2mg & Phenylephrine HCl 5mg (Sugar Free)

Form : SYRUP / Pack : 100ml / Type : Bottle

Description : Dextromethorphan HBr is a semi-synthetic morphinan analogue, shows high affinity to several regions of the brain, including the medullary cough center thus widely used as an anti-tussives. Hence prevents unproductive coughing.

Chlorpheniramine Maleate is a synthetic alkylamine derivative acts as a competitive H1- receptor antagonist and displays anticholinergic and mild sedative effects as well.

Phenylephrine HCl is an alpha-1 adrenergic agonist causes vasoconstriction in the management of nasal congestion.

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