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Uricosuric agents should be used in most patient after ongoing urate deposition has been confirmed and attempts to correct or reverse other causes of hyperuricemia have been made. Inhibitors of uric acid synthesis are also used, particularly for patients who produce excessive amounts of urate (more than 800 mg in 24 hours) - Journal of Pharmacy & Therapeutics, Vol, 35 (2) 2010, Feb.
Gout was associated with increased risk of cancer particularly that of prostate cancer in males - Joint Bone Spine, Volume, 79, Issue 4, July 2012, Pages 375-378
febuxostat is an effective option for treatement of hyperuricemia in patients with gout, as it was more effective and faster at achieving target sUA levels than allopurinol - Arthritis Research & Therapy, 2015, 17:120
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