A Superior gastro-prokinetic agent of the benzamide class

Composition : Cinitapride 1mg

Form : Tablets / Pack : 10 x 10's / Type : ALU-ALU

Description : Cinitapride, either given alone or after co-administration with ketoconazole 200 mg b.i.d., had no effect on cardiac repolarization as measured by changes in the heart rate-corrected QT interval on the surface electrocardiogram - Drug Metab Dispos. 2007 Jul;35(7):1149-56.

After 4 weeks of treatment, the Global Index Score showed statistically significant reduction in 58 (48.92%) patients (p<0.01). Similar reduction (p<0.01) was seen in individual dyspepsia symptoms; early satiety, post-prandial fullness, and abdominal distension. The 7 point Likert's scale also showed similar improvement in subjective response (p<0.01).The quality of life also improved significantly at week 2 and 4 (p<0.01). No abnormal results were seen in vital signs, physical and laboratory examination except an unexplained rise in globulin level. Only one adverse event (sore throat) was reported during the study - J Pak Med Assoc. 2013 Jun; 63(6):747-51

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